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CARDIOVASCULAR JOURNAL OF AFRICA • Volume 29, No 2, March/April 2018

AFRICA

111

For abnormal glucose level with increasing BMI, the chances

of having abnormal glucose level increased 2.5 times (OR 2.39;

5% CI: 1.33–4.30;

p

=

0.004). Other variables such as physical

activity, number of driving hours, waist circumference and

professional driving years were not independently associated

with our outcome parameters and were excluded from the final

regression model.

Discussion

The major finding of this study was that male long-distance bus

drivers had a higher prevalence of clustering of cardiometabolic

risk factors than the general population, and in addition, most

them were unaware of their risk status.

12,14

This clustering places

them at a higher risk for CVD and contributes significantly to

the already burgeoning CVD burden in the general population.

Importantly, a CVD event in a driver while driving portends

grave danger to him, the passengers and other road users.

The prevalence of hypertension in this study was 39.7%,

with 75.9% being newly diagnosed. This is higher than the

recent pooled national prevalence rate of 28.9% but lower than

the 44.9% prevalence from a national study on blindness and

hypertension.

32,33

Previous local studies reported prevalence rates

ranging from 21.4 to 33.5%.

19-21

Studies from Brazil and Iran

reported prevalence rates of 45.6 and 44.6%, respectively, much

higher than their national prevalence rates.

12,13

Professional drivers, by nature of their occupation, are

largely sedentary and indulge in dietary indiscretions, which

could lead to obesity. From this study, obesity was a predictor of

hypertension. Furthermore, BMI and longer duration of years

of professional driving significantly correlated with the risk

of hypertension, similar to findings by Sangaletti

et al

.

12

This

association is plausible, as drivers who drive for long hours over

many years tend to gain weight inappropriately due to physical

inactivity and dietary indiscretion.

In addition to high prevalence of hypertension, optimal blood

pressure control was equally low among the subjects. Among the

9.6% previously known hypertensives, only 21.4% had optimal

BP control. BP control is generally very low in Nigeria, ranging

between five and 29.4%.

34,35

Ignorance, long travel times, poor

access to standard medical care, the asymptomatic nature of

hypertension and the relative lack of self-care among males have

been suggested as possible causes of poor BP control among

long-distance drivers.

12

The prevalence of abnormal glucose profiles in this study

was 45.2%, comprising 31.3 and 13.9% for impaired fasting

gliucose levels and diabetes mellitus (DM), respectively. Most

of the diabetics were diagnosed for the first time during this

study. There are no local studies for comparison but the reported

prevalence of DM from this study is much higher than the 4.5%

reported by the International Diabetes Federation (IDF) and the

eight to 10% from a study on the general population.

36,37

In Iran,

Table 4. Association between independent variables and

hypertension and abnormal glucose levels

Hypertension

Abnormal glucose levels

Parameter

% (95% CI)

p

-value % (95% CI)

p

-value

Driving hours/week

0.250

0.076

36

42.9 (35.0–50.9)

35.6 (27.9–43.2)

<

36

36.3 (28.5–44.2)

25.9 (18.6–33.2)

Years of professional driving

<

0.001

0.320

20

56.2 (43.1–64.4)

33.1 (25.4–40.8)

<

20

23.1 (16.2–30.0)

27.7 (20.3–35.0)

Physical activity

0.279

0.205

<

600 METs/week

42.6 (34.6–50.5)

27.6 (20.3-34.9)

600 METs/week

36.3 (28.5–44.2)

34.5 (26.7-42.3)

BMI

<

0.001

0.002

Overweight/obese

48.4 (41.1–55.6)

37.8 (30.7–44.9)

Normal

25.9 (17.7–34.2)

19.8 (12.2–27.4

Alcohol use

0.840

0.807

Yes

40.1 (33.4–46.8)

31.2 (24.9–37.6)

No

38.8 (28.5–49.2)

29.8 (20.0–39.5)

Smoking

0.477

0.808

Yes

43.9 (31.0–56.7)

32.1 (19.9-44.4)

No

38.7 (28.5-49.2)

30.5 (24.6-36.4)

WC (cm)

<

0.001

0.076

>

102

61.4 (50.0–72.8)

39.7 (28.1–51.3)

102

33.0 (26.8–39.2)

28.3 (22.3–34.3)

Age

<

0.001

0.499

45

54.5 (46.4–62.6)

32.6 (25.0–40.3)

<

45

25.2 (18.2–32.2)

29.0 (21.6–36.3)

BMI: body mass index; WC: waist circumference; METs: metabolic equivalents.

HTN,

abnormal glucose,

high WC, smoking,

high TC/HDL

HTN,

abnormal glucose,

high WC, smoking

HTN,

abnormal glucose,

high WC

HTN,

abnormal glucose,

smoking

HTN,

abnormal glucose,

TC/HDL ratio

HTN,

abnormal glucose

None

59 (20.1%)

36 (12.3%)

8 (2.73%)

8 (2.73%)

14 (4.8%)

4

1

n

= 293 (%)

0 5 10 15 20 25 30 35 40

Fig. 6.

Prevalence of different combinations of risk factors in

the subjects. HTN: hypertension; WC: waist circumfer-

ence; TC: total cholesterol; HDL: high-density lipopro-

tein cholesterol.

Table 5. Logistic regression on predictors of hypertension and

abnormal glucose levels

Hypertension

a

Abnormal glucose levels

b

Variables

OR (95% CI)

p

-value OR (95% CI)

p

-value

Age

1.090 (1.058–1.23)

<

0.0001

ns

ns

Overweight/obesity 2.99 (1.69–5.32)

<

0.0001 2.39 (1.33–4.3)

0.04

a

Variables excluded from the final model were: physical activity, number of driv-

ing hours, waist circumference and professional driving years.

b

Variables excluded from the final model were: age, physical activity, number of

driving hours, waist circumference and professional driving years.