The primary aim of this consensus is to identify strategies for diagnosing, treating, and managing heart failure in Africa.
Volume 36, Issue 3
Secondary prevention and management of dyslipidaemia in patients with coronary artery disease on statin therapy in a tertiary academic centre in Johannesburg
Optimal low-density lipoprotein cholesterol (LDL-C) control in patients with established atherosclerotic cardiovascular disease (ASCVD) is defined as LDL-C levels less than 1.4 mmol/L and a reduction of >50% in baseline LDL-C levels. This study aims to assess LDL-C control in patients with ASCVD on statin treatment in a tertiary academic hospital.
A massive cardiac tumor
Myxoma is the most common cardiac tumor, typically found in the left atrium. Here, we present a case of a large right atrial myxoma.
Insights into cardiovascular health: patient perspectives from a South African tertiary hospital
Cardiovascular disease (CVD) remains one of the preventable causes of death. Increasing patient knowledge of CVD may lead to success in the prevention and control of CVD, and an improved quality of life.
Delta perfusion rate predicts the development of adverse outcome in cardiopulmonary bypass patients
Despite the advances in CPB, various complications may occur. Prediction and anticipation of these undesirable outcomes is of great importance. For this reason, various markers have been tried to be determined.
Right ventricular function, pulmonary hypertension and incident mortality in heart failure: Insights from a West-African cohort
Few studies have assessed the prevalence and independent prognostic relevance of right ventricular dysfunction (RVD) and pulmonary hypertension (PH) in Africans with heart failure (HF) despite the different trajectories of HF in Africans compared to other ethnicities. We investigated the frequency and independent associations of RVD and PH with incident death in Nigerian-Africans with...
Krüppel-like factor 5 transcription factor is a positive regulator of NRG-1 in human coronary artery smooth muscle cells
Structural remodelling of the heart and blood vessels is an important basis for the development of cardiovascular disease. Krüppel-like factor 5 (KLF5), an important regulator of cardiovascular remodelling, promotes vascular smooth muscle cell (VSMC) proliferation and inflammatory responses. Neuregulin 1 (NRGI) is a positive regulator of angiogenesis, and its receptors are human epidermal growth...
Exploring the influence of risk factors on outcomes following surgical closure of ventricular septal defects
Surgical closure of ventricular septal defects remains the predominant paediatric cardiac surgical intervention. This study aims to identify risk factors influencing the duration of intensive care stay and complications following surgical correction for ventricular septal defects.
Impact of posterior pericardiectomy vs. posterior pericardial Hemovac drainage on POAF and fluid management in CABG patients
This study compares posterior pericardiectomy (PP) and posterior pericardial Hemovac drainage (PPHD) in terms of their effects on post-operative atrial fibrillation (POAF) incidence in patients undergoing coronary artery bypass grafting (CABG).
Repolarisation disturbances in ischaemic stroke: unveiling the prognostic role of the frontal QRS-T angle
Ischaemic stroke is frequently associated with electrocardiographic (ECG) abnormalities, including repolarisation disturbances. These disturbances, often seen as prolonged QT intervals or altered T-wave morphology, reflect impaired ventricular repolarisation and have been linked to an increased risk of cardiovascular events. One specific marker, the frontal QRS-T angle (FQRS-T angle), which...

