This systematic review protocol describes the proposed method for evaluating evidence from original articles to understand the benefits, opportunities, and challenges of using data science for non-communicable disease (NCD) prevention and control in Africa.
Cardiovascular Topics
Clinical characteristics and short-term outcomes of patients with STEMI treated by percutaneous coronary intervention in a military hospital in Senegal
The prevalence of in-hospital acute coronary syndrome (ACS) has risen from 4% to 10% in Dakar cardiology departments over the past 15 years, while the management of patients with persistent ST-segment elevation myocardial infarction (STEMI) has improved thanks to the availability of catheterisation laboratories in multiple hospitals of the Senegalese capital, including our centre at Hôpital...
Sex differences in mortality and hospitalisation in heart failure patients: sex differences in heart failure.
We aimed to investigate the clinical and demographic characteristics, and mortality differences between male and female patients with heart failure (HF) with reduced ejection fraction (HFrEF) admitted to our hospital.
Urinary dopamine, sodium handling, and blood pressure in a bi-ethnic South African population: the SABPA study
Urinary dopamine is associated with increased sodium excretion in experimental studies, and possibly contributes to blood pressure (BP) regulation and salt- sensitivity. Studies in humans are limited, and the potential association with potassium is unclear. We aimed to compare urinary dopamine/creatinine ratio and investigate the associations of urinary dopamine/creatinine ratio with BP, sodium...
Do preoperative low triiodothyronine levels affect early kidney injury after coronary artery bypass grafting? A retrospective study
Acute kidney injury is a common complication of cardiac surgery, and factors such as advanced age, diabetes mellitus, and low left ventricular function are reported to be risk factors for the development of acute kidney injury after coronary artery bypass grafting (CABG). There are few studies in the literature reporting the relationship between preoperative low T3 syndrome and cardiac surgery...
The relationship between the electromechanical window and ventricular arrhythmia prevalence in HFrEF patients with ICD
The electromechanical window (EMW) refers to the time interval between aortic valve closure and the end of the T-wave during the same cardiac cycle. Recent studies highlight the role of EMW in assessing the risk of ventricular arrhythmia. This study examines the predictive value of the EMW for ventricular arrhythmias in heart failure with reduced ejection fraction (HFrEF) patients with an...
Effect of resting heart rate on coronary collateral formation in patients with chronic total occlusion: resting heart rate and collaterals
In this study our aim was to determine the effect of resting heart rate (HR) on the development of coronary collateral circulation (CCC) in patients with chronic total occlusion (CTO).
Hypertension treatment practices and outcomes at health community centres in urban Soweto, South Africa
In this study, we explored hypertension (HT) management in urban Soweto, South Africa, involving 364 participants from primary healthcare clinics. At baseline, 40% of participants were prescribed one drug, and 53% were given two drugs.
Evaluation of the effects of dapagliflozin on subclinical atherosclerosis with two non-invasive methods: pulse wave velocity and carotid intima-media thickness
Recent cardiovascular outcome trials have shown that sodium-glucose co-transporter 2 (SGLT2) inhibitors reduce cardiovascular events, but results regarding their effects on subclinical atherosclerosis are conflicting. In this study, we aimed to investigate the effect of dapagliflozin, a selective SGLT2 inhibitor, on subclinical atherosclerosis by monitoring pulse wave velocity (PWV) and carotid...
Effect of metoprolol and bisoprolol on bleeding rates in patients with atrial fibrillation
Atrial fibrillation (AF) is a complex disease with irregular ventricular response and tachycardia as a result of irregular and rapid contraction of the atria, with poor cardiovascular outcomes unless treated. Beta-blockers are commonly used agents in the treatment of AF. The effects of beta-blockers on bleeding continue to be evaluated.

