Cardiovascular Journal of Africa

Cardiovascular Topics

Association of preoperative systemic immune-inflammation index and atherogenic index of plasma with early postoperative clinical outcomes in patients undergoing isolated elective coronary artery bypass grafting with cardiopulmonary bypass

Coronary artery disease (CAD) is a complex cardiovascular condition associated with multifaceted pathophysiological mechanisms such as inflammation, thrombotic activation, endothelial dysfunction, and an atherogenic lipid profile.

Admission neutrophil-to-lymphocyte ratio and target-vessel failure after bifurcation percutaneous coronary intervention in acute coronary syndrome

Coronary bifurcation lesions represent one of the most complex settings in patients with acute coronary syndrome (ACS) and are associated with worse outcomes after percutaneous coronary intervention (PCI). In addition to anatomical complexity, systemic inflammation may influence long-term vessel-related outcomes. The neutrophil-to-lymphocyte ratio (NLR) is a simple marker of inflammatory burden...

Neurological and neurocognitive outcomes of routine deep hypothermic circulatory arrest with open distal anastomosis in ascending aortic and aortic root aneurysm surgery

This study aimed to evaluate postoperative neurological and neurocognitive changes in patients undergoing ascending aortic and aortic root aneurysm surgery using the deep hypothermic circulatory arrest technique with open distal anastomosis performed without cerebral perfusion.

Diagnostic performance of computed tomography-derived fractional flow reserve in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: a single-centre feasibility study

Coronary artery disease (CAD) is prevalent in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI). Computed tomography-derived fractional flow reserve (CT-FFR) may provide non-invasive functional assessment using existing TAVI planning imaging to evaluate CT-FFR diagnostic performance compared with invasive coronary angiography (ICA) for identifying...

Awake off-pump no-touch aorta coronary artery bypass grafting in a patient with interstitial lung disease during the COVID-19 pandemic

Off-pump coronary artery bypass grafting (OPCABG) is favoured to reduce surgical trauma during myocardial revascularisation. Severe chronic respiratory conditions, such as interstitial lung disease, are known to significantly complicate perioperative management and long-term survival. For patients with a history of serious chronic respiratory or advanced respiratory disease, awake OPCABG under...

Factors associated with cerebrovascular complications in a cohort of patients with autosomal dominant polycystic kidney disease in South Africa

The prevalence of intracranial aneurysms (IAs) in individuals with autosomal dominant polycystic kidney disease (ADPKD) is about 6%–25%. This rate is higher than that of the general population and is associated with increased morbidity and mortality. Studies in Africa are sparse. Therefore, we aimed to describe the clinical manifestations, imaging features, and long-term prognoses of patients...