Takayasu arteritis (TA) is commonly known as a disease of young women, highly prevalent in Asia and Central America, and associated with multiple vascular complications. Although it is well described in the paediatric population, severe complications are rarely seen.
Volume 37, Issue 4
A new biomarker to assess cardiac involvement in children with acute rheumatic fever: Growth differentiation factor-15
We aimed to investigate the role of growth differentiation factor-15 (GDF-15) in acute rheumatic carditis by evaluating its correlations with acute-phase reactants and echocardiographic values.
5,924 views
3 min read
The prognostic value of combined blood indices of systemic inflammation in heart failure with reduced ejection fraction
We aimed to evaluate the relationship of the aggregate index of systemic inflammation (AISI) and the systemic inflammation response index (SIRI) – defined as combined systemic inflammation indices – with one-year mortality and major adverse cardiovascular events (MACE) in patients with heart failure with reduced ejection fraction (HFrEF).
5,922 views
3 min read
iCARDIO Alliance Global Implementation Guidelines on Heart Failure 2026
This is the updated 2026 version of the iCARDIO Alliance Global Implementation Guidelines on Heart Failure – originally published in 2025. In these guidelines, we aim to consider inconsistencies in healthcare access, varying infrastructure, resource constraints and diverse local practices as well as practical and political issues that restrict the global applicability of currently available...
1,168 views
4 min read
Unusual coexistence of vascular compression syndromes: Nutcracker, Dunbar, and May–Thurner syndromes
Vascular compression syndromes represent a group of rare conditions caused by extrinsic compression of veins or arteries by surrounding anatomical structures. These disorders are often underdiagnosed due to nonspecific symptoms, and the coexistence of multiple syndromes in a single patient is extremely rare.
6,008 views
2 min read
Temporary arterial clamping in major musculoskeletal malignant tumour surgery: A two-centre comparative study
The aim of this study was to assess the safety of temporary arterial clamping in major musculoskeletal malignant tumour surgery and its impact on blood loss and related complications.
5,908 views
3 min read
MTHFR C677T polymorphism and hyperhomocysteinaemia as determinants of acute myocardial infarction severity in the Batak ethnic population: A case–control study using the Gensini score
Elevated homocysteine is a recognized cardiovascular risk marker, and the MTHFR C677T polymorphism a determinant of its concentration; yet data from Indonesian populations are scarce.
5,896 views
3 min read
Examination of acquired coagulopathy in patients with aortic stenosis
Aortic stenosis (AS) is one of the cardiovascular diseases with an increasing prevalence and is associated with high morbidity. In this patient population, bleeding diathesis represents a significant challenge in clinical management.
5,911 views
3 min read
Safety and patient comfort after coronary artery bypass surgery: Conventional versus single-drain – a retrospective cohort study
This study aimed to evaluate whether on-pump coronary artery bypass grafting (CABG) using the left internal mammary artery can be safely performed without pleural drain placement and whether this approach improves postoperative comfort by reducing pain and pulmonary complications.
5,906 views
2 min read
Infective endocarditis in children: a 23-year experience at a Southern African tertiary institution
There is a paucity of data regarding infective endocarditis (IE) in children, particularly in low-to-middle-income settings, with minimal recent data from Sub-Saharan Africa.
5,908 views
2 min read