Cardiovascular Journal of Africa

Volume 37, Issue 3

False-negative 99mTc-PYP bone scintigraphy in early cardiac amyloidosis: a rapidly progressive case in a young woman

Cardiac amyloidosis is one of the aetiologies of treatable heart failure. Cardiac amyloidosis is rare in young patients, but it can present atypically, leading to diagnostic delays. In this case, a 33-year-old female patient presenting with dyspnoea underwent echocardiography and cardiac magnetic resonance imaging, which showed left ventricular hypertrophy and raised suspicion for amyloidosis;...

Mechanical vs. sutureless aortic valve replacement: clinical outcomes and the contribution of preoperative multislice CT

Heart valve disease is a significant cause of morbidity and mortality, and aortic valve replacement (AVR) is a common treatment option. Recently, sutureless biological valves have gained increasing use. This study aimed to evaluate the concordance between preoperative computed tomography-derived annulus measurements and valve sizes implanted during surgery rather than the direct clinical impact...

Admission serum bicarbonate is associated with early diuretic resistance in acute decompensated heart failure

Acute decompensated heart failure (ADHF) exhibits a heterogeneous diuretic response. Chloride-bicarbonate imbalance may reduce loop diuretic efficiency. The effect of admission bicarbonate levels on diuretic resistance in unselected ADHF patients remains unclear. We aimed to evaluate whether higher admission bicarbonate identifies patients at risk of early diuretic dose escalation and less...

Aggressive surgical approach in diffuse coronary artery disease: coronary endarterectomy and early- to mid-term outcomes

In patients with diffuse coronary artery disease (CAD), the absence of a suitable distal target vessel for standard coronary artery bypass grafting (CABG) is the main factor limiting the success of surgical revascularisation. The aim of this study was to evaluate the surgical outcomes, complication profile, and functional recovery of a high-risk patient cohort who underwent single or multiple...

Association and causality between triglycerides and hypertension: evidence from NHANES 2007–2018 and two-sample Mendelian randomisation analysis

Hypertension is a major global health issue, and elevated triglyceride levels may be an independent risk factor. However, existing studies are limited, and the association remains unclear across diverse populations. This study uses the National Health and Nutrition Examination Survey (NHANES) data to investigate this association, supporting hypertension prevention and management strategies.