Cardiovascular Journal of Africa

A novel marker for determining the severity of coronary artery disease: the metabolic coronary risk index

Yücel Kanal, Idris Yakut
Abstract
Abstract: Despite advances in prevention and treatment, coronary artery disease (CAD) remains a major cause of death globally. Glycated haemoglobin (HbA1c) and body mass index (BMI) are known risk factors for CAD. This study aimed to investigate the relationship between the metabolic coronary risk index (MCRI) and the severity of CAD, measured by the SYNTAX score (SS), in patients with acute coronary syndrome (ACS) who underwent coronary angiography (CAG). A total of 214 patients were included, with a mean age of 59.29 ± 11.93 years, and 25.7% were female. Regression analysis showed thatMCRI independently predicted CAD severity. MCRI differentiated moderate and high SS from low SS with 70% sensitivity and 50% specificity at a cutoff value of 158.9. The study concluded that MCRI is a significant predictor of CAD severity in ACS patients.
Keywords: HbA1c, body mass index, coronary artery disease, acute coronary syndrome, percutaneous coronary intervention
Submitted: October 21, 2024; Accepted: November 25, 2025; Published: June 30, 2025
Cardiovasc J Afr 2025; 36: 129-133
Volume 36, Issue 2
DOI Citation Reference: dx.doi.org/10.5830/CVJA-2025-011
Cumhuriyet University, Department of Cardiology, Turkey
Yücel Kanal, Asst Prof
Istanbul Medipol University, Department of Cardiology, Turkey
Idris Yakut, Asst Prof

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