Cardiovascular Journal of Africa

The relationship between coronary complexity and triglyceride glucose index in stable coronary artery disease

Oguz Kilic, Damla Yalcinkaya Oner, Fatma Ozpamuk Karadeniz, Emine Altuntas, Ercan Erdogan
Abstract
Aim: Coronary artery disease (CAD) is an important health problem and accurate prognostic evaluations are critical. We aimed to investigate the association between the triglyceride glucose (TyG) index and coronary complexity in stable CAD patients.
Methods: We retrospectively enrolled 247 stable CAD patients. The patient group was classified into two groups; group 1: SYNTAX 0, group 2: SYNTAX ≥1. TyG index levels were analysed in these groups.
Results: A total of 247 patients were included in the study. Group 1 included 106 patients and, group 2 included 141 patients. Mean age was 68.9 ± 10.6 and 52.2% was male. TyG index was statistically significantly higher in group 2 (p < 0.001).Correlation analysis showed a strong correlation between the TyG index and SYNTAX score (r = 0.303, p < 0.001).
Conclusion: It was observed that high TyG index values increased the complexity of lesions in coronary arteries. The TyG index may be used to determine the prognosis of patients.
Keywords: Triglyceride-Glucose Index, coronary artery disease, insulin resistance, coronary complexity assessment
Submitted: February 17, 2025; Accepted: April 7, 2025; Published: October 17, 2025
Cardiovasc J Afr 2025; 36: 451-455
Volume 36, Issue 4
DOI Citation Reference: dx.doi.org/10.5830/CVJA-2025-064
Cardiology Department, Karamanoglu Mehmetbey University, Karaman Research and Training Hospital, Karaman, Turkey
Oguz Kilic
Fatma Ozpamuk Karadeniz
Ercan Erdogan

Department of Cardiology, Karaman Training and Research Hospital, Karaman, Turkey
Damla Yalcinkaya Oner

Department of Cardiology, University of Health Sciences, Istanbul Mehmet Akif Ersoy Thoracic Cardiovascular Surgery Health Application and Research Center, Istanbul, Turkey
Emine Altuntas

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