Cardiovascular Journal of Africa

Anomalous aortic origin of the coronary arteries: a presentation of three cases and review of the literature

Anisa Rafique Essop, Mohammed Zaid Moosa, Ahmed Rashid Essop, Martin John Sussman, Jonathan Hack, Mohammed Rafique Essop
Abstract
In this retrospective review of three patients presenting with anomalous aortic origin of the coronary arteries (AAOCA), we sought to highlight the varying presentations, discuss the optimal diagnostic imaging strategy and review current guidelines on the management of this condition. Over a one-year period three patients with AAOCA were identified. Pertinent data were extracted from case records and imaging, management and outcomes were reviewed in detail. All three patients had an anomalous right coronary artery originating from the left coronary sinus (AORCA) as well as a malignant course between the aorta and pulmonary artery. Although conventional angiography suggested the diagnosis, CT coronary angiography (CTA) was more useful in describing the anatomy and course of the anomalous artery and determining the necessity for and guidance to the type of surgical intervention required. All three patients underwent successful surgery. A brief literature review of the implications and management of this condition is provided.
Keywords: anomalous coronary artery, computed tomography, management
Submitted: November 28, 2024; Accepted: July 11, 2025; Published: October 17, 2025
Cardiovasc J Afr 2025; 36: 499-504
Volume 36, Issue 4
DOI Citation Reference: dx.doi.org/10.5830/CVJA-2025-072
Charlotte Maxeke Academic Hospital, Johannesburg, South Africa
Anisa Rafique Essop

Cardiology, Milpark Hospital, Johannesburg, South Africa
Mohammed Zaid Moosa
Ahmed Rashid Essop
Mohammed Rafique Essop

Cardiothoracic Surgery, Milpark Hospital, Johannesburg South Africa
Martin John Sussman

Radiology, Sunninghill Hospital, Johannesburg, South Africa
Jonathan Hack

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