Cardiovascular Journal of Africa

Data science applications for non-communicable disease prevention and control in Africa: a systematic review protocol

Akinkunmi Paul Okekunle, Muideen Tunbosun Olaiya, Paul Olowoyo, Grace Ajuwon, Alison Annet Kinengyere, Judit Kumuthini, Osahon Jeffery Asowata, Onoja Matthew Akpa, Adekunle Fakunle, Shakuntala Baichoo, Folakemi Odedina, Yosr Hamdi, Charles Agyemang, Bruce Ovbiagele, Mayowa Owolabi
Abstract
Aim: This systematic review protocol describes the proposed method for evaluating evidence from original articles to understand the benefits, opportunities, and challenges of using data science for non-communicable disease (NCD) prevention and control in Africa.
Methods: Literature searches will be implemented in five scientific databases and one search engine using predefined keywords/MeSH terms to identify relevant articles. At least two reviewers will independently screen, appraise, extract, and summarise data from eligible articles using predefined inclusion criteria.
Results: This systematic review will consider primary studies from articles that applied data science methods (such as artificial intelligence, machine learning, and risk or prognosis model algorithms, among others) to address NCD prevention and control exclusively among Indigenous Africans.
Conclusion: Findings from this systematic review could serve as a roadmap to guide future initiatives to apply data science methods to revolutionise NCD prevention and control in Africa.
Keywords: machine learning, artificial intelligence, non-communicable diseases, surveillance, Africa
Submitted: July 10, 2024; Accepted: April 30, 2025; Published: November 28, 2025
Cardiovasc J Afr 2025; 36: 603-611
Volume 36, Issue 4
DOI Citation Reference: dx.doi.org/10.5830/CVJA-2025-085
Department of Medicine, College of Medicine, University of Ibadan, 200284, Nigeria.
Akinkunmi Paul Okekunle
Adekunle Fakunle
Mayowa Owolabi

Research Institute of Human Ecology, Seoul National University, 08826, Korea.
Akinkunmi Paul Okekunle

School of Clinical Sciences, Monash University, Clayton, VIC, Australia.
Muideen Tunbosun Olaiya

College of Medicine and Health Sciences, Afe Babalola University, Nigeria.
Paul Olowoyo

E. Latunde Odeku Medical Library, College of Medicine, University of Ibadan, 200284, Nigeria.
Grace Ajuwon

Sir Albert Cook Library, College of Health Sciences, Makerere University, Kampala, Uganda.
Alison Annet Kinengyere

South African National Bioinformatics Institute, University of Western Cape, South Africa.
Judit Kumuthini

Department of Epidemiology and Medical Statistics, University of Ibadan, 200284, Nigeria.
Osahon Jeffery Asowata
Onoja Matthew Akpa

Department of Digital Technologies, FoICDT, University of Mauritius, Reduit, Mauritius.
Shakuntala Baichoo

Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, United States.
Folakemi Odedina

Laboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, 1002 Tunisia.
Yosr Hamdi

Amsterdam Public Health Research Institute, Department of Public & Occupational Health, Amsterdam University Medical Center, University of Amsterdam, 1105AZ Amsterdam.
Charles Agyemang

Weill Institute for Neurosciences, University of California San Francisco, United States.
Bruce Ovbiagele

Center for Genomic and Precision Medicine, College of Medicine, University of Ibadan, 200284, Nigeria.
Mayowa Owolabi

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