Copyright: Clinics Cardive Publishing (Pty) Ltd. publisher
of Cardiovascular Journal of Africa.
Abstract
Introduction:
Persistent left superior vena cava (PLSVC) is a congenital vascular anomaly that is often asymptomatic and typically discovered incidentally. In this case, the patient had a known cardiac anomaly, and PLSVC was diagnosed following cardiological suspicion.
Case: A 38-year-old female patient was evaluated for chronic exertional dyspnea. Chest radiography revealed enlargement of the upper and anterior mediastinum. Contrast-enhanced thoracic computed tomography confirmed the presence of PLSVC. Echocardiography showed that the PLSVC drained into the right atrium via an enlarged coronary sinus. The patient was also being followed for an atrial septal defect, cardiomyopathy, and an interatrial aneurysm. Additionally, she was diagnosed with asthma, and appropriate treatment was initiated.
Conclusion: Enlargement of the upper and anterior mediastinum on chest radiography, the presence of a dilated coronary sinus on echocardiography, and/or associated congenital cardiac anomalies should prompt consideration of PLSVC. Recognising this anomaly prior to invasive procedures is critical, as it may lead to unexpected complications.
Case: A 38-year-old female patient was evaluated for chronic exertional dyspnea. Chest radiography revealed enlargement of the upper and anterior mediastinum. Contrast-enhanced thoracic computed tomography confirmed the presence of PLSVC. Echocardiography showed that the PLSVC drained into the right atrium via an enlarged coronary sinus. The patient was also being followed for an atrial septal defect, cardiomyopathy, and an interatrial aneurysm. Additionally, she was diagnosed with asthma, and appropriate treatment was initiated.
Conclusion: Enlargement of the upper and anterior mediastinum on chest radiography, the presence of a dilated coronary sinus on echocardiography, and/or associated congenital cardiac anomalies should prompt consideration of PLSVC. Recognising this anomaly prior to invasive procedures is critical, as it may lead to unexpected complications.
Keywords:
Persistent left superior vena cava, atrial septal defect, mediastinal widening, asthma
Submitted: August 28, 2025;
Accepted: September 16, 2025;
Published: February 20, 2026
Cardiovasc J Afr 2025; 37: 49-52
Volume 37, Issue 1
Cardiovasc J Afr 2025; 37: 49-52
Volume 37, Issue 1
DOI Citation Reference: dx.doi.org/10.5830/CVJA-2025-106

