Cardiovascular Journal of Africa

Assessment of the aortic root and ascending aorta in swine using CTA

Xiaoyu Gao, Negin Hadijabdolhamid, Nile Khai Luu, Alesh Ruben Polvika, Sabee Molloi
Abstract
Purpose: Swine are widely recognised as an essential experimental platform for evaluating prosthetic heart valves and testing novel catheter-based deployment methods. Our study aimed to establish baseline normative diameters for the aortic root and ascending aorta in swine using spiral computed tomography angiography (CTA), enhancing the success of preclinical research and device development.
Methods: Our study involved thoracic CTA scans of 34 male swine, detailing the anatomical features of the aortic root and ascending aorta, and measuring the diameters at five key planes.
Results: We conducted an additional analysis of the relationships among the chosen principal parameters.
Conclusion: The baseline angiography of swine offers reference values for future studies.
Keywords: computed tomography angiography, cardiovascular disease, aortic root, ascending aorta, swine
Submitted: February 14, 2025; Accepted: January 21, 2026; Published: May 8, 2026
Cardiovasc J Afr 2025; 37: 165-172
Volume 37, Issue 2
DOI Citation Reference: dx.doi.org/10.5830/CVJA-2026-003
Department of Radiology, Suzhou Health Vocational College, Suzhou City, China
Xiaoyu Gao

Department of Radiological Sciences, University of California, Irvine, California, USA
Negin Hadijabdolhamid
Nile Khai Luu
Alesh Ruben Polvika
Sabee Molloi

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