Cardiovascular Journal of Africa

iCARDIO Alliance Global Implementation Guidelines on Heart Failure 2025

Inconsistencies in healthcare access, varying infrastructure, resource constraints and diverse local practices as well as practical and political issues restrict the global applicability of currently available guidelines. The iCARDIO Alliance Global Implementation Guidelines on Heart Failure 2025 offers updated, practical recommendations for...

Welcome to the Cardiovascular Journal of Africa

The Cardiovascular Journal of Africa (CVJA) is an international peer-reviewed journal that keeps cardiologists up to date with advances in the diagnosis and treatment of cardiovascular disease. Topics covered include coronary disease, electrophysiology, valve disease, imaging techniques, congenital heart disease (fetal, paediatric & adult), heart failure, surgery & basic science. CVJA is the official journal of the Pan-African Society of Cardiology (PASCAR) and has been published since 1990.

If you need to refer back to the old CVJA platform, visit this link: https://cvja.co.za/index.php

Important Notice to all Authors:

Manuscript Submission Fee & Article Processing Charge (updated March 2026)


It has become necessary for the Cardiovascular Journal of Africa to charge a manuscripts submission fees for all articles submitted for publication. On acceptance of a manuscript an additional Article Processing Fee will apply before publishing.


    From the Editor-in-Chief

    Professor Paul Brink

    At the Cardiovascular Journal of Africa (CVJA), the editorial team and I are excited to welcome you to our new redesigned website. This represents a significant step forward in our ongoing mission to serve as a trusted, accessible, and comprehensive resource for the cardiovascular community across Africa and beyond.

    Our updated digital platform has been thoughtfully developed to enhance your experience whether you are reading the latest research, submitting a manuscript, or browsing through archived issues. With improved navigation, faster access to content, and mobile-friendly features, we aim to make high-quality cardiovascular knowledge more accessible than ever before.

    As a peer-reviewed and indexed journal, CVJA, continues to publish a wide range of original articles, reviews, case reports, and editorials spanning all aspects of cardiovascular medicine. From clinical practice and public health to cardiovascular imaging, surgery, and basic science, we are proud to reflect the full spectrum of inquiry that drives progress in our field.


    We invite clinicians, researchers, and scholars from across the continent and the world to engage with our content, contribute their findings, and join us in advancing cardiovascular care) through science and collaboration.

    Thank you for your continued support of CVJA. We look forward to growing together and adapting. Time does not stand still. As Bob Dylan, still around and reinventing himself, sang in the 6’s – “The Times They Are A-Changin'”

    Latest News

    Global Heart Failure Guidelines 2025 – Now Published!

    The iCARDIO Alliance Global Implementation Guidelines on Heart Failure 2025 are now available, proudly co-published by Global Cardiology and the Cardiovascular Journal of Africa. Developed by a truly international panel of experts, these guidelines address the diverse challenges of heart failure care worldwide, particularly in regions with limited healthcare resources.

    This comprehensive guideline offers updated, practical recommendations for diagnosing and managing acute and chronic heart failure, including context-specific options for both pharmacological and non-pharmacological treatment. Importantly, it introduces resource-adjusted strategies, enabling clinicians to make effective decisions even in low- and middle-income settings. By combining the latest evidence with global collaboration, these guidelines aim to reduce hospitalisations, improve outcomes, and support clinicians everywhere in delivering better heart failure care.

    Read the full guidelines here »

    Latest articles

    Admission serum bicarbonate is associated with early diuretic resistance in acute decompensated heart failure

    Acute decompensated heart failure (ADHF) exhibits a heterogeneous diuretic response. Chloride-bicarbonate imbalance may reduce loop diuretic efficiency. The effect of admission bicarbonate levels on diuretic resistance in unselected ADHF patients remains unclear. We aimed to evaluate whether higher admission bicarbonate identifies patients at risk of early diuretic dose escalation and less...

    Aggressive surgical approach in diffuse coronary artery disease: coronary endarterectomy and early- to mid-term outcomes

    In patients with diffuse coronary artery disease (CAD), the absence of a suitable distal target vessel for standard coronary artery bypass grafting (CABG) is the main factor limiting the success of surgical revascularisation. The aim of this study was to evaluate the surgical outcomes, complication profile, and functional recovery of a high-risk patient cohort who underwent single or multiple...

    Association and causality between triglycerides and hypertension: evidence from NHANES 2007–2018 and two-sample Mendelian randomisation analysis

    Hypertension is a major global health issue, and elevated triglyceride levels may be an independent risk factor. However, existing studies are limited, and the association remains unclear across diverse populations. This study uses the National Health and Nutrition Examination Survey (NHANES) data to investigate this association, supporting hypertension prevention and management strategies.