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CARDIOVASCULAR JOURNAL OF AFRICA • Volume 28, No 2, March/April 2017

AFRICA

91

INTERHEART study investigators. Obesity and the risk of myocardial

infarction in 27,000 participants from 52 countries: a case- control study.

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Proc Nutr Soc

2015; Feb 17: 1–9 Epub ahead

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. Optimal cut-

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doi:10.2105/AJPH.2005.062059.

Confidence Through Clinical

and Real World Experience

1-3

Millions of Patients Treated Across Multiple Indications

4

#1 NOAC prescribed by Cardiologists

*

*Impact RX Data Oct - Dec 2015

NOAC: Non Vitamin K Oral Anticoagulant

REFERENCES: 1.

Patel M.R., Mahaffey K.W., Garg J.

et al.

Rivaroxaban versus warfarin in non-valvular atrial fi brillation.

N Engl J Med

. 2011;365(10):883–91.

2.

Tamayo S., Peacock W.F., Patel M.R.,

et al.

Characterizing major bleeding in patients

with nonvalvular atrial fi brillation: A pharmacovigilance study of 27 467 patients taking rivaroxaban.

Clin Cardiol

. 2015;38(2):63–8.

3.

Camm A.J., Amarenco P., Haas S.

et al.

XANTUS: A Real-World, Prospective, Observational Study.

4.

Calculation

based on IMS Health MIDAS, Database: Monthly Sales December 2015.

S4 XARELTO

®

15: Each film-coated tablet contains rivaroxaban 15 mg. Reg. No: 46/8.2/0111; Namibia S2 : 12/8.2/0006; Botswana S2 : BOT1302296

S4 XARELTO

®

20: Each film-coated tablet contains rivaroxaban 20 mg. Reg. No: 46/8.2/0112; Namibia S2 : 12/8.2/0007; Botswana S2 : BOT1302297

PHARMACOLOGICAL CLASSIFICATION:

A.8.2 Anticoagulants.

INDICATIONS:

(1) Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (SPAF); (2) Treatment of deep vein thrombosis (DVT) and for the prevention

of recurrent deep vein thrombosis (DVT) and pulmonary embolism (PE); (3) Treatment of pulmonary embolism (PE) and for the prevention of recurrent pulmonary embolism (PE) and deep vein thrombosis (DVT).

HCR:

Bayer (Pty) Ltd, Co. Reg. No.:

1968/011192/07, 27 Wrench Road, Isando, 1609. Tel: +27 (0) 11 921 5044 Fax: +27 (0) 11 921 5041. For full prescribing information, refer to the package insert approved by the Medicines Regulatory Authority (MCC).

L.ZA.MKT.GM.01.2016.1265

© Bayer January 2016