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CARDIOVASCULAR JOURNAL OF AFRICA • Volume 32, No 4, July/August 2021

AFRICA

203

generalisations cannot be drawn to all of Khartoum state, only

to populations with characteristics similar to those of the sample.

Since no standardised tool for assessing knowledge and

practice of patients towards lifestyle changes exists, the

researcher designed the questionnaire based on the literature

and what would be applicable to the study population. Hence

the comparison of results between different studies is difficult.

Another limitation was that implementation of lifestyle changes

was assessed by yes/no questions and no varying degrees of

implementation were reported, which may have made the results

less accurate.

Conclusion

This study demonstrated that hypertensive patients were

generally knowledgeable about hypertension and the importance

of TLC in its management, particularly the importance of

minimising salt intake. Patients implemented regular exercise

least often and gave ‘don’t think it matters’ or ‘laziness’ as their

main perceived barrier. Participants gave this reason despite

ample knowledge of lifestyle changes and being advised by

doctors on these changes. This was deduced since no association

was found between patients’ level of knowledge or duration of

consultation and their degree of implementation of lifestyle

change. The researcher believes that novel approaches are

needed to help motivate patients diagnosed with hypertension

apply their knowledge regarding TLC.

The author recommends more comprehensive research on

this topic to accurately ascertain patients’ perception of TLC as

adjuncts to pharmacological therapy. Once patients’ perceived

barriers are better understood, novel and more effective

approaches to consultation may then be developed and applied.

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Inter-arm difference in blood pressure robustly linked to greater early death risk

Robust evidence from a large meta-analysis published in

Hypertension

confirms that a difference in blood pressure

readings between arms is linked to greater risk of heart

attack, stroke and death. The study provides a new upper

limit of ‘normal’ for an inter-arm difference in blood pressure,

which is significantly lower than the current guidance.

Led by the University of Exeter, the global INTERPRESS-

IPD collaboration conducted a meta-analysis of all the

available research, then merged data from 24 global studies to

create a database of nearly 54 000 people. The data spanned

adults from Europe, the USA, Africa and Asia for whom

blood pressure readings for both arms were available.

Funded by the National Institute for Health Research

(NIHR), the study is the first to conclude that the greater the

inter-arm blood pressure difference, the greater the patient’s

additional health risk.

Currently, international blood pressure guidelines advise

health professionals to measure blood pressure in both arms

when assessing cardiovascular risk, yet this is widely ignored.

This study provides a new upper limit of ‘normal’ for an

inter-arm difference in blood pressure, which is significantly

lower than the current guidance. The research could lead

to a change in international hypertension guidelines,

meaning more at-risk patients could be identified and receive

potentially life-saving treatment.

In a methodology that put patients at its heart, working

with a patient advisory group at every step of the research, the

team analysed data on inter-arm blood pressure difference,

and tracked the number of deaths, heart attacks and strokes

that occurred in the cohort over 10 years.

Lead author and GP Dr Chris Clark, of the University

of Exeter Medical School, said: ‘Checking one arm then

the other with a routinely used blood pressure monitor

is cheap and can be carried out in any healthcare setting,

without the need for additional or expensive equipment. While

international guidelines currently recommend that this is done,

it only happens around half of the time at best, usually due to

time constraints. Our research shows that the little extra time it

takes to measure both arms could ultimately save lives.’

continued on page 223 …