Cardiovascular Journal of Africa

Cardiovascular Topics

Validity testing of the novel European Society of Cardiology EURObservational Research Programme PPCM Registry score to predict left ventricular recovery in a cohort of Ugandan women with PPCM

Recently under the European Society of Cardiology (ESC) EURObservational Research Programme (EORP) PPCM registry the first predictive score was derived. This study sought to test the validity of this predictive score in a cohort of women with PPCM in Uganda.

A comparative analysis of the effects of moderate vs mild hypothermia on serum neuron-specific enolase, S100β, and near-infrared spectroscopy during cardiopulmonary bypass-assisted open-heart surgery: a single-centre study

Neurological injury remains a critical concern in cardiac surgery despite advancements in surgical and anaesthetic techniques. Hypothermia is commonly utilised for neuroprotection during cardiopulmonary bypass (CPB); however, the optimal temperature range remains undetermined. This study evaluates the neuroprotective effectiveness of mild versus moderate hypothermia by assessing neuron-specific...

The effects of chronic administration of Cannabidiol and Cannabidiol-Selexipag combination on haematological parameters, oxidative stress, BNP, and TNF-α in a rat model of Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a progressive disorder characterized by pulmonary vasoconstriction and inflammation, leading to increased pulmonary pressure, right heart failure, and high mortality. Cannabidiol (CBD), a non-psychoactive cannabinoid, exhibits anti-inflammatory and antioxidant properties. This study investigates the therapeutic potential of CBD, alone and in combination...

Efficacy of using 50 mL syringe manual thrombectomy catheter in patients with heavy thrombus burden undergoing primary percutaneous coronary intervention

Patients with ST-segment elevation myocardial infarction (STEMI) and heavy thrombus burden are at increased risk of distal embolisation and impaired reperfusion during primary percutaneous coronary intervention (PPCI). Conventional manual aspiration thrombectomy with a 30 mL syringe has shown limited benefit in large randomised trials. Increasing syringe volume to 50 mL may enhance suction...

Kinesiophobia and associated variables in patients with atrial fibrillation combined with heart failure: A cross-sectional study from China

While kinesiophobia is a recognised phenomenon in global cardiovascular rehabilitation, its prevalence and characteristics remain unexplored in the specific and growing population of patients hospitalised with atrial fibrillation and heart failure (AFHF). This study aims to investigate the prevalence of kinesiophobia and to identify its associated factors among hospitalised AFHF patients in...

Assessment of the aortic root and ascending aorta in swine using CTA

Swine are widely recognised as an essential experimental platform for evaluating prosthetic heart valves and testing novel catheter-based deployment methods. Our study aimed to establish baseline normative diameters for the aortic root and ascending aorta in swine using spiral computed tomography angiography (CTA), enhancing the success of preclinical research and device development.