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CARDIOVASCULAR JOURNAL OF AFRICA • Volume 27, No 4, July/August 2016

AFRICA

269

32. Spence JD. Carotid plaque measurement is superior to IMT: Invited

editorial comment on: Carotid plaque, compared with carotid intima–

media thickness, more accurately predicts coronary artery disease events:

A meta-analysis. Inaba Y, Chen JA, Bergmann SR.

Atherosclerosis

2012;

220

: 34–35.

33. Wang KL, Cheng HM, Chuang SY, Spurgeon HA, Ting C, Lakatta EG,

et al.

Central or peripheral systolic or pulse pressure: which best relates

to target organs and future mortality?

J Hypertens

2009;

27

: 461–467.

34. Sliwa K, Wilkinson D, Hansen C, Ntyintyane L, Tibazarwa K, Becker

A,

et al

. Spectrum of heart disease and risk factors in a black urban

population in South Africa (The Heart of Soweto study): a cohort study.

Lancet

2008;

371

: 915–922.

35. Fowkes FGR, ThorogoodM, Connor MP, Lewando-Hundt G, Tzoulaki

I, Tollman SM. Distribution of a subclinical marker of cardiovascular

risk, the ankle brachial index, in a rural African population: SASPI

study.

Eur J Cardiovasc Prev Rehabil

2006;

13

: 964–969.

36. Vorster HH. The emergence of cardiovascular disease during urbanisa-

tion of Africans.

Public Health Nutr

2002;

5

: 239–243.

37. Sun P, Dwyer KM, Merz CNB, Sun W, Johnson CA, Shircore AM,

et

al

. Blood pressure, LDL cholesterol, and intima–media thickness: A test

of the “Response to injury” hypothesis of atherosclerosis.

Arterioscler

Thromb Vasc Biol

2000;

20

: 2005–2010.

38. Yang C, Sun Z, Li Y, Ai J, Sun Q, Tian Y. The correlation between serum

lipid profile with carotid intima–media thickenss and plaque.

BMC

Cardiocasc Discord

2014;

14

: 181.

39. McEniery CM, Wilkinson IB. Large artery stiffness and inflammation.

J Hum Hypertens

2005;

19

: 507–509.

40. Preston RA, Jy W, Jimenez JJ, Mauro LM, Horstman LL, Valle M,

et al

.

Effects of severe hypertension on endothelial and platelet microparticles.

Hypertension

2003;

41

: 211–217.

41. Caviezel S, Dratva J, Schaffner E, Schindler C, Zemp Stutz E, de

Groot E,

et al.

Sex-specific associations of cardiovascular risk factors

with carotid stiffness – Results from the SAPALDIA Cohort Study.

Atherosclerosis

2014;

235

: 576–584.

Confidence Through Clinical

and Real World Experience

1-3

Millions of Patients Treated Across Multiple Indications

4

#1 NOAC prescribed by Cardiologists

*

References:

1.

Patel M.R., Mahaffey K.W., Garg J.

et al.

Rivaroxaban versus warfarin in non-valvular atrial fibrillation.

N Engl J Med

. 2011;365(10):883–91.

2.

Tamayo S., Peacock W.F., Patel M.R.,

et al.

Characterizing major bleeding in patients with nonvalvular atrial fibrillation: A pharmacovigilance study of 27 467 patients taking rivaroxaban.

Clin Cardiol

. 2015;38(2):63–8.

3.

Camm A.J., Amarenco P., Haas S.

et al.

XANTUS: A Real-World,

Prospective, Observational Study.

4.

Calculation based on IMS Health MIDAS, Database: Monthly Sales December 2015.

For fullprescribing information,refer to thepackage insertapprovedby theMedicinesRegulatoryAuthority (MCC). S4 XARELTO

®

10 (Film-coated tablets)

.Reg.No.

:42/8.2/1046.Eachfilm-coated tabletcontainsrivaroxaban10mg.

PHARMACOLOGICALCLASSIFICATION:

A.8.2Anticoagulants.

INDICATION:

Prevention of venous thromboembolism (VTE) in patients undergoing major orthopaedic surgery of the lower limbs. S4 XARELTO

®

15 and XARELTO

®

20 (Film-coated tablets). Reg. No.: XARELTO

®

15: 46/8.2/0111; XARELTO

®

20: 46/8.2/0112. Each film

coated tablet contains rivaroxaban 15 mg (XARELTO

®

15) or 20 mg (XARELTO

®

20).

PHARMACOLOGICAL CLASSIFICATION:

A.8.2 Anticoagulants.

INDICATIONS:

(1) Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation (SPAF); (2)

Treatment of deep vein thrombosis (DVT) and for the prevention of recurrent deep vein thrombosis (DVT) and pulmonary embolism (PE); (3) Treatment of pulmonary embolism (PE) and for the prevention of recurrent pulmonary embolism (PE) and deep vein thrombosis (DVT).

HCR:

Bayer (Pty) Ltd, Reg. No.: 1968/011192/07, 27 Wrench Road, Isando, 1609. Tel: 011 921 5044 Fax: 011 921 5041.

L.ZA.MKT.GM.01.2016.1265

*Impact RX Data Oct - Dec 2015

NOAC: Non Vitamin K Oral Anticoagulant