It was aimed to investigate the patients who underwent coronary artery bypass grafting with coronary endarterectomy (CABG-CE) and postoperative dual antiplatelet therapy (DAPT) in terms of acute coronary syndrome, mortality and morbidity in the early period.
Cardiovascular Topics
Assessment of the aortic root and ascending aorta in swine using CTA
Swine are widely recognised as an essential experimental platform for evaluating prosthetic heart valves and testing novel catheter-based deployment methods. Our study aimed to establish baseline normative diameters for the aortic root and ascending aorta in swine using spiral computed tomography angiography (CTA), enhancing the success of preclinical research and device development.
Association between Epstein-Barr Virus viremia and cardiac function in children and young adults with perinatally acquired HIV
Epstein-Barr virus (EBV) affects greater than 95% of the global population, and when acquired at an early age, results in poor control of viral replication and increased risk to subsequent chronic illnesses.
Association of ACE I/D and ACE (rs4343) polymorphism with MACE development in hypertensive patients
Cardiovascular diseases remain a leading cause of morbidity and mortality worldwide. The angiotensin-converting enzyme (ACE) insertion/deletion (I/D) and ACE rs4343 polymorphism have been considered important and extensively studied for their association with cardiovascular conditions. This study investigates the association of this variant with the development of major adverse cardiovascular...
The Medium and Long-Term Effects of COVID-19 on the Non-Dipper Blood Pressure Pattern
Although the COVID-19 pandemic has ended, its long-term cardiovascular effects remain unclear. This study evaluated persistent changes in blood pressure (BP) patterns among recovered COVID-19 patients.
A nomogram model for predicting risk of lower extremity deep venous thrombosis in patients after heart valve replacement
We aimed to construct and validate a nomogram model for predicting the risk of lower extremity deep venous thrombosis (DVT) in patients after heart valve replacement. The data of patients hospitalised for heart valve replacement between January 2021 and March 2024 were retrospectively analysed.
Predictive Value of the Endothelial Activation and Stress Index for No-Reflow in NSTEMI Patients Undergoing Percutaneous Coronary Intervention
The no-reflow phenomenon, defined as inadequate myocardial perfusion despite successful epicardial recanalisation, remains a major complication after PCI in NSTEMI. Endothelial dysfunction and microvascular injury are key mechanisms. The Endothelial Activation and Stress Index (EASIX), calculated as (LDH × creatinine) / platelet count, reflects systemic endothelial stress and may predict no...
Intra- and inter-rater reproducibility of the echocardiographic data of the Nigerian UPRIGHT-HTM trial participants
Echocardiography is the guideline- recommended tool for risk stratification in asymptomatic high-risk patients, but its reproducibility in sub-Saharan Africa remains largely undocumented. This study assessed the intra- and inter-rater repeatability of the risk-carrying echocardiographic traits among 42 patients enrolled in the UPRIGHT-HTM trial at three Nigerian sites.
Clinical and echocardiographic characteristics of patients presenting with pulmonary hypertension due to congenital heart disease
This study aimed to assess patients’ clinical and echocardiographic features in pulmonary hypertension (PH) due to congenital heart disease (CHD).
Development of National Anticoagulation Guidelines for Pregnant Women with Mechanical Heart Valves in Rwanda
The number of Rwandan women of reproductive age receiving mechanical heart valve prostheses for rheumatic heart disease is increasing. Effective anticoagulation management during pregnancy is essential to prevent valve thrombosis but poses significant risks to both mother and foetus if not carefully tailored.

