The advantages of direct oral anticoagulants (apixaban, rivaroxaban, edoxaban, dabigatran) over warfarin and low molecular weight heparin have been demonstrated in many studies in the treatment of patients with acute venous thromboembolism (VTE). However, a single-centre study comparing the effectiveness and safety of oral anticoagulants against each other has not yet been conducted.
Cardiovascular Topics
Patient education in cardiovascular disease in Sub-Saharan Africa: the “Heart School” pilot project at IPMS/Cheikh Anta Diop University of Dakar, Senegal
To describe a patient education (PE) pilot project named “the Heart School” at Cheikh Anta Diop University of Dakar.
Pre-operative MELD-Na score as an independent predictor of post-operative mortality after valve surgery in rheumatic valvular heart disease patients
Rheumatic heart disease (RHD) poses a significant global health challenge due to its high rates of premature morbidity, mortality, and disability, particularly in low-income countries. Existing risk scoring systems for valve replacement in cardiac surgery have primarily focused on non-RHD cases, making them less applicable to RHD patients due to the distinct pathology of valvular damage. This...
Prognostic value of dobutamine stress echocardiography: A South African experience
Dobutamine stress echocardiography (DSE) is a well-established modality for the diagnosis and risk-stratification of coronary artery disease, but no prognostic data have been reported from Southern Africa.
Predictive efficiency of serum fibrinogen and D-Dimer levels for left ventricular remodelling after acute myocardial infarction
We aimed to explore serum D-dimer plus fibrinogen (FIB) levels in acute myocardial infarction (AMI) for their efficiency in predicting subsequent left ventricular remodelling (LVRM).
The relationship between symptomatic lower extremity peripheral artery disease with carotid artery stenosis and ischemic stroke
The aim of this study was to investigate the prevalence of carotid artery stenosis (CAS) in peripheral artery disease (PAD) patients requiring surgical or interventional procedures, to examine the clinical relationship between CAS and PAD, and to determine the characteristics of ischemic stroke developing within a one-year postoperative period.
Mid-term results of bicuspid aortic valve repair with a new technique, the Ozbek procedure
Aortic valve insufficiency has been reported in approximately one-third of patients with a bicuspid aortic valve (BAV). In this study, we describe a new use of an old aortic repair technique and report its mid-term results.
The early-term effects of the minimally invasive extracorporeal circulation on atrial fibrillation development in patients who underwent coronary artery bypass grafting
The minimised extracorporeal circulation (MiECC) system is an alternative to the classical extracorporeal circulation (ECC) system in coronary artery bypass grafting (CABG) surgery. Some publications reported that there are few studies on the relationship between this application and the development of postoperative atrial fibrillation (POAF) and that differences in results were observed. We...
Validity testing of the novel European Society of Cardiology EURObservational Research Programme PPCM Registry score to predict left ventricular recovery in a cohort of Ugandan women with PPCM
Recently under the European Society of Cardiology (ESC) EURObservational Research Programme (EORP) PPCM registry the first predictive score was derived. This study sought to test the validity of this predictive score in a cohort of women with PPCM in Uganda.
A comparative analysis of the effects of moderate vs mild hypothermia on serum neuron-specific enolase, S100β, and near-infrared spectroscopy during cardiopulmonary bypass-assisted open-heart surgery: a single-centre study
Neurological injury remains a critical concern in cardiac surgery despite advancements in surgical and anaesthetic techniques. Hypothermia is commonly utilised for neuroprotection during cardiopulmonary bypass (CPB); however, the optimal temperature range remains undetermined. This study evaluates the neuroprotective effectiveness of mild versus moderate hypothermia by assessing neuron-specific...

