Cardiovascular Journal of Africa

Cardiovascular Topics

Evaluation of six-month clinical outcomes of patients with venous thromboembolism treated with apixaban, rivaroxaban, edoxaban or dabigatran

The advantages of direct oral anticoagulants (apixaban, rivaroxaban, edoxaban, dabigatran) over warfarin and low molecular weight heparin have been demonstrated in many studies in the treatment of patients with acute venous thromboembolism (VTE). However, a single-centre study comparing the effectiveness and safety of oral anticoagulants against each other has not yet been conducted.

Pre-operative MELD-Na score as an independent predictor of post-operative mortality after valve surgery in rheumatic valvular heart disease patients

Rheumatic heart disease (RHD) poses a significant global health challenge due to its high rates of premature morbidity, mortality, and disability, particularly in low-income countries. Existing risk scoring systems for valve replacement in cardiac surgery have primarily focused on non-RHD cases, making them less applicable to RHD patients due to the distinct pathology of valvular damage. This...

The relationship between symptomatic lower extremity peripheral artery disease with carotid artery stenosis and ischemic stroke

The aim of this study was to investigate the prevalence of carotid artery stenosis (CAS) in peripheral artery disease (PAD) patients requiring surgical or interventional procedures, to examine the clinical relationship between CAS and PAD, and to determine the characteristics of ischemic stroke developing within a one-year postoperative period.

The early-term effects of the minimally invasive extracorporeal circulation on atrial fibrillation development in patients who underwent coronary artery bypass grafting

The minimised extracorporeal circulation (MiECC) system is an alternative to the classical extracorporeal circulation (ECC) system in coronary artery bypass grafting (CABG) surgery. Some publications reported that there are few studies on the relationship between this application and the development of postoperative atrial fibrillation (POAF) and that differences in results were observed. We...

Validity testing of the novel European Society of Cardiology EURObservational Research Programme PPCM Registry score to predict left ventricular recovery in a cohort of Ugandan women with PPCM

Recently under the European Society of Cardiology (ESC) EURObservational Research Programme (EORP) PPCM registry the first predictive score was derived. This study sought to test the validity of this predictive score in a cohort of women with PPCM in Uganda.

A comparative analysis of the effects of moderate vs mild hypothermia on serum neuron-specific enolase, S100β, and near-infrared spectroscopy during cardiopulmonary bypass-assisted open-heart surgery: a single-centre study

Neurological injury remains a critical concern in cardiac surgery despite advancements in surgical and anaesthetic techniques. Hypothermia is commonly utilised for neuroprotection during cardiopulmonary bypass (CPB); however, the optimal temperature range remains undetermined. This study evaluates the neuroprotective effectiveness of mild versus moderate hypothermia by assessing neuron-specific...